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RAB20 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NX57 |
| Other Accession | NP_060287.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26277 Da |
| Antigen Region | 202-229 aa |
| Gene ID | 55647 |
|---|---|
| Other Names | Ras-related protein Rab-20, RAB20 |
| Target/Specificity | This RAB20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the C-terminal region of human RAB20. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RAB20 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RAB20 |
|---|---|
| Function | Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. |
| Cellular Location | Golgi apparatus. Cytoplasmic vesicle, phagosome Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) {ECO:0000250|UniProtKB:P35295, ECO:0000269|PubMed:21255211} |
| Tissue Location | Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
RAB20 plays a role in apical endocytosis/recycling.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Das Sarma, J., et al. Cell Commun. Adhes. 15(1):65-74(2008)
Amillet, J.M., et al. Hum. Pathol. 37(3):256-263(2006)
Pereira-Leal, J.B., et al. J. Mol. Biol. 313(4):889-901(2001)
Lutcke, A., et al. J. Cell. Sci. 107 (PT 12), 3437-3448 (1994) :
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