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RBM11 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P57052 |
| Other Accession | NP_658983.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 32179 Da |
| Antigen Region | 28-54 aa |
| Gene ID | 54033 |
|---|---|
| Other Names | Splicing regulator RBM11, RNA-binding motif protein 11, RBM11 |
| Target/Specificity | This RBM11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-54 amino acids from the N-terminal region of human RBM11. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RBM11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RBM11 (HGNC:9897) |
|---|---|
| Function | Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1. |
| Cellular Location | Nucleus, nucleoplasm. Nucleus speckle. Note=Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles |
| Tissue Location | Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
RBM11, also known as RNA binding motif protein 11, is a human gene. 2 isoforms of the human protein are produced by alternative splicing.
References
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Lim, J., et al. Cell 125(4):801-814(2006)
Brun, M.E., et al. Gene 312, 41-50 (2003) :
Gardiner, K., et al. Genomics 79(6):833-843(2002)
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