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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RGL4 Antibody (N-term)   

RGL4 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RGL4 Antibody (N-term) AP17597A
    RGL4 Antibody (N-term) (Cat. #AP17597a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the RGL4 antibody detected the RGL4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IZJ4
Other Accession NP_705843.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 52346 Da
Antigen Region 98-125 aa
Additional Information
Gene ID 266747
Other Names Ral-GDS-related protein, hRGR, Ral guanine nucleotide dissociation stimulator-like 4, RalGDS-like 4, RGL4, RGR
Target/Specificity This RGL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-125 amino acids from the N-terminal region of human RGL4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRGL4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGL4
Synonyms RGR
Cellular Location Cytoplasmic vesicle.
Research Areas
Citations (0)

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Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL4 (ral guanine nucleotide dissociation stimulator-like 4), also known as Rgr, is a 473 amino acid protein that localizes to the cytoplasmic vesicle of cells. Belonging to the GEF family of proteins, RGL4 induces phosphorylation of ERKs, p38 and JNK kinases, and it increases the levels of GTP bound forms of Ral and Ras. Ras activation is crucial for the transforming activity of RGL4. Due to its similarity to Ral GDS, RGL4 may be implicated in carcinogenesis.


Hernandez-Munoz, I., et al. Cancer Res. 63(14):4188-4195(2003)
Hernandez-Munoz, I., et al. Oncogene 19(23):2745-2757(2000)
Dunham, I., et al. Nature 402(6761):489-495(1999)
D'Adamo, D.R., et al. Oncogene 14(11):1295-1305(1997)

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$ 295.00
$ 99.00
Cat# AP17597A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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