SERINC2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q96SA4 |
Other Accession | NP_849196.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 50742 Da |
Antigen Region | 289-316 aa |
Gene ID | 347735 |
---|---|
Other Names | Serine incorporator 2, Tumor differentially expressed protein 2-like, SERINC2, TDE2L |
Target/Specificity | This SERINC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-316 amino acids from the Central region of human SERINC2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SERINC2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SERINC2 |
---|---|
Synonyms | TDE2L |
Cellular Location | Membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
SERINC2 is a member of a family of carrier proteins, Serinc 1-5, that incorporate a polar amino acid serine into membranes and facilitate the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. The Serinc family is a unique protein family that shows no amino acid homology to other proteins but is highly conserved among eukaryotes. The members contain 11 transmembrane domains, similar to amino acid transporters.
References
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Player, A., et al. Int. J. Cancer 107(2):238-243(2003)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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