|Application ||WB, E|
|Calculated MW||39309 Da|
|Antigen Region||319-345 aa|
|Other Names||Inhibitor of nuclear factor kappa-B kinase-interacting protein, I kappa-B kinase-interacting protein, IKBKB-interacting protein, IKK-interacting protein, IKBIP, IKIP|
|Target/Specificity||This IKBIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-345 amino acids from the C-terminal region of human IKBIP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IKBIP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Target of p53/TP53 with pro-apoptotic function.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization|
|Tissue Location||Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
Target of TP53/p53 with pro-apoptotic function.
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hofer-Warbinek, R., et al. Cell Death Differ. 11(12):1317-1325(2004)
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