|Application ||WB, E|
|Calculated MW||39309 Da|
|Antigen Region||319-345 aa|
|Other Names||Inhibitor of nuclear factor kappa-B kinase-interacting protein, I kappa-B kinase-interacting protein, IKBKB-interacting protein, IKK-interacting protein, IKBIP, IKIP|
|Target/Specificity||This IKBIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-345 amino acids from the C-terminal region of human IKBIP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IKBIP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Target of p53/TP53 with pro-apoptotic function.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization|
|Tissue Location||Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Target of TP53/p53 with pro-apoptotic function.
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hofer-Warbinek, R., et al. Cell Death Differ. 11(12):1317-1325(2004)
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