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MYH7 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MYH7 Antibody (N-term) AP17633a
    Anti-MYH7 Antibody (N-term) at 1:1000 dilution + human skeletal muscle lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 223 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - MYH7 Antibody (N-term) AP17633a
    MYH7 Antibody (N-term) (Cat. #AP17633a) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MYH7 antibody detected the MYH7 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P12883
Other Accession NP_000248.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 223097 Da
Antigen Region 185-211 aa
Additional Information
Gene ID 4625
Other Names Myosin-7, Myosin heavy chain 7, Myosin heavy chain slow isoform, MyHC-slow, Myosin heavy chain, cardiac muscle beta isoform, MyHC-beta, MYH7, MYHCB
Target/Specificity This MYH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the N-terminal region of human MYH7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMYH7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYH7
Synonyms MYHCB
Function Muscle contraction.
Cellular Location Cytoplasm, myofibril. Note=Thick filaments of the myofibrils
Tissue Location Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level)
Research Areas
Citations (0)

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Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.


Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) :
Eijgelsheim, M., et al. Hum. Mol. Genet. 19(19):3885-3894(2010)
Millat, G., et al. Eur J Med Genet 53(5):261-267(2010)
Muelas, N., et al. Neurology 75(8):732-741(2010)
Zheng, D.D., et al. J. Int. Med. Res. 38(3):810-820(2010)

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$ 295.00
$ 99.00
Cat# AP17633a
(40 western blots)
Availability: In Stock
Bulk Size
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