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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RNF14 Antibody (C-term)   

RNF14 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RNF14 Antibody (C-term) AP17648b
    RNF14 Antibody (C-term) (Cat. #AP17648b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RNF14 antibody detected the RNF14 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBS8
Other Accession NP_899646.1, NP_004281.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53837 Da
Antigen Region 336-364 aa
Additional Information
Gene ID 9604
Other Names E3 ubiquitin-protein ligase RNF14, 632-, Androgen receptor-associated protein 54, HFB30, RING finger protein 14, Triad2 protein, RNF14, ARA54
Target/Specificity This RNF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the C-terminal region of human RNF14.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRNF14 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNF14
Synonyms ARA54
Function Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.
Cellular Location Cytoplasm. Nucleus
Tissue Location Widely expressed.
Research Areas
Citations (0)

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The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.


Xu, K., et al. Cancer Cell 15(4):270-282(2009)
Lan, K.C., et al. Fertil. Steril. 89 (5 SUPPL), 1397-1405 (2008) :
Kikuchi, H., et al. Carcinogenesis 28(8):1752-1758(2007)
Yang, Z., et al. Endocrinology 148(3):1340-1349(2007)
Yang, Z., et al. Mol. Endocrinol. 21(2):343-358(2007)

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$ 295.00
$ 99.00
Cat# AP17648b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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