SHISA5 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8N114 |
Other Accession | NP_057563.3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 25582 Da |
Antigen Region | 75-102 aa |
Gene ID | 51246 |
---|---|
Other Names | Protein shisa-5, Putative NF-kappa-B-activating protein 120, Scotin, SHISA5, SCOTIN |
Target/Specificity | This SHISA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the Central region of human SHISA5. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SHISA5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SHISA5 |
---|---|
Synonyms | SCOTIN |
Function | Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis. |
Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane |
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Provided below are standard protocols that you may find useful for product applications.
Background
SHISA5 can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
References
So, H.C., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (1), 103-113 (2010) :
Draeby, I., et al. Arch. Biochem. Biophys. 467(1):87-94(2007)
Ludes-Meyers, J.H., et al. Oncogene 23(29):5049-5055(2004)
Matsuda, A., et al. Oncogene 22(21):3307-3318(2003)
Bourdon, J.C., et al. J. Cell Biol. 158(2):235-246(2002)
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