|Application ||WB, E|
|Calculated MW||42772 Da|
|Antigen Region||8-36 aa|
|Other Names||Oxytocin receptor, OT-R, OXTR|
|Target/Specificity||This OXTR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human OXTR.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OXTR Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition.
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Kim, H.S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15717-15721(2010)
Thompson, R.J., et al. Psychoneuroendocrinology (2010) In press :
Tost, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13936-13941(2010)
Amrani, Y., et al. Respir. Res. 11, 104 (2010) :
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