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GRSF1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GRSF1 Antibody (Center) AP17673c
    GRSF1 Antibody (Center) (Cat. #AP17673c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the GRSF1 antibody detected the GRSF1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q12849
Other Accession Q8C5Q4, NP_002083.3
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53126 Da
Antigen Region 307-333 aa
Additional Information
Gene ID 2926
Other Names G-rich sequence factor 1, GRSF-1, GRSF1
Target/Specificity This GRSF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-333 amino acids from the Central region of human GRSF1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGRSF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRSF1
Function Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences.
Cellular Location Cytoplasm. Mitochondrion matrix, mitochondrion nucleoid. Note=Forms granules that colocalize with foci of newly synthesized mtRNA next to mitochondrial nucleoids
Citations (0)

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The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene.


Kash, J.C., et al. J. Virol. 76(20):10417-10426(2002)
Park, Y.W., et al. Proc. Natl. Acad. Sci. U.S.A. 96(12):6694-6699(1999)
Banga, S.S., et al. Cytogenet. Cell Genet. 73(4):295-296(1996)
Qian, Z., et al. Nucleic Acids Res. 22(12):2334-2343(1994)

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Cat# AP17673c
(40 western blots)
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