|Application ||WB, E|
|Other Accession||Q66HG3, Q8BUG2, NP_116038.4|
|Calculated MW||56706 Da|
|Antigen Region||142-170 aa|
|Other Names||Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase, CNDP1, CN1, CPGL2|
|Target/Specificity||This CNDP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-170 amino acids from the Central region of human CNDP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CNDP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Found in serum and adult nervous central system. Absent in serum from patients with homocarnosinosis|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region.
Alkhalaf, A., et al. Diabetologia (2010) In press :
Riedl, E., et al. Diabetes 59(8):1984-1990(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Mooyaart, A.L., et al. Diabetes 59(6):1555-1559(2010)
Kim, S., et al. Clin J Am Soc Nephrol 5(6):1072-1078(2010)
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