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SCNN1D Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SCNN1D Antibody (N-term) AP17675A
    SCNN1D Antibody (N-term) (Cat. #AP17675a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SCNN1D antibody detected the SCNN1D protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P51172
Other Accession NP_002969.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 70215 Da
Antigen Region 161-189 aa
Additional Information
Gene ID 6339
Other Names Amiloride-sensitive sodium channel subunit delta, Delta-NaCH, Epithelial Na(+) channel subunit delta, Delta-ENaC, ENaCD, Nonvoltage-gated sodium channel 1 subunit delta, SCNED, SCNN1D, DNACH
Target/Specificity This SCNN1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the N-terminal region of human SCNN1D.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSCNN1D Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SCNN1D
Synonyms DNACH
Function Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Background

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

References

Wesch, D., et al. Am. J. Physiol., Cell Physiol. 299 (4), C779-C790 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Bangel-Ruland, N., et al. Am. J. Respir. Cell Mol. Biol. 42(4):498-505(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Haerteis, S., et al. J. Biol. Chem. 284(42):29024-29040(2009)

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$ 295.00
$ 99.00
Cat# AP17675A
Size:
Quantity:
(40 western blots)
Availability: In Stock
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