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NDST3 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NDST3 Antibody (C-term) AP17676B
    NDST3 Antibody (C-term) (Cat. #AP17676b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NDST3 antibody detected the NDST3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95803
Other Accession Q9EQH7, NP_004775.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 100902 Da
Antigen Region 809-836 aa
Additional Information
Gene ID 9348
Other Names Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3, Glucosaminyl N-deacetylase/N-sulfotransferase 3, NDST-3, hNDST-3, N-heparan sulfate sulfotransferase 3, N-HSST 3, Heparan sulfate N-deacetylase 3, 3---, Heparan sulfate N-sulfotransferase 3, 282-, NDST3, HSST3
Target/Specificity This NDST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 809-836 amino acids from the C-terminal region of human NDST3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNDST3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NDST3
Synonyms HSST3
Function Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Expressed in brain, kidney, liver, fetal and adult lung, adult pancreas, placenta, fetal spleen and fetal thymus. Not detected in adult/ fetal heart and skeletal muscle
Citations (0)

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This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin.


Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Krenn, E.C., et al. Biochem. Biophys. Res. Commun. 375(3):297-302(2008)
Grobe, K., et al. Biochim. Biophys. Acta 1573(3):209-215(2002)

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$ 295.00
$ 99.00
Cat# AP17676B
(40 western blots)
Availability: In Stock
Bulk Size
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