ZNF224 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9NZL3 |
Other Accession | NP_037530.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 82280 Da |
Antigen Region | 127-155 aa |
Gene ID | 7767 |
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Other Names | Zinc finger protein 224, Bone marrow zinc finger 2, BMZF-2, Zinc finger protein 233, Zinc finger protein 255, Zinc finger protein 27, Zinc finger protein KOX22, ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27 |
Target/Specificity | This ZNF224 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the N-terminal region of human ZNF224. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ZNF224 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZNF224 |
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Synonyms | BMZF2, KOX22, ZNF233, ZNF255, ZNF27 |
Function | May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. |
Cellular Location | Nucleus Note=Colocalizes with DEPDC1A at the nucleus |
Tissue Location | Ubiquitous. Mainly expressed in fetal tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF224 may be involved in transcriptional regulation as a transcriptional repressor.
References
Harada, Y., et al. Cancer Res. 70(14):5829-5839(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Shulman, J.M., et al. PLoS ONE 5 (6), E11244 (2010) :
Cesaro, E., et al. J. Biol. Chem. 284(47):32321-32330(2009)
Iacobazzi, V., et al. Biochem. Biophys. Res. Commun. 386(1):186-191(2009)
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