CYB5D1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q6P9G0 |
Other Accession | NP_653208.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 26689 Da |
Antigen Region | 59-86 aa |
Gene ID | 124637 |
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Other Names | Cytochrome b5 domain-containing protein 1, CYB5D1 |
Target/Specificity | This CYB5D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the Central region of human CYB5D1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CYB5D1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CYB5D1 (HGNC:26516) |
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Function | Radial spoke stalk protein that binds heme under oxidizing conditions. Required for the coordinated beating of multiple cilia maybe by functioning in a redox signaling pathway. |
Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q567I9}. Note=Localizes to the radial spoke stalk. {ECO:0000250|UniProtKB:Q567I9} |
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Provided below are standard protocols that you may find useful for product applications.
Background
CYB5D1 belongs to the cytochrome b5 family and contains 1 cytochrome b5 heme-binding domain. Cytochromes b5 are ubiquitous electron transport proteins found in animals, plants and yeasts. There are 2 named isoforms produced by alternative splicing.
References
Ota, T., et al. Nat. Genet. 36(1):40-45(2004)
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