|Application ||WB, E|
|Calculated MW||20747 Da|
|Antigen Region||53-80 aa|
|Other Names||Dynactin subunit 6, Dynactin subunit p27, Protein WS-3, DCTN6, WS3|
|Target/Specificity||This DCTN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the Central region of human DCTN6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DCTN6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known.
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Parisi, G., et al. FEBS Lett. 562 (1-3), 1-4 (2004) :
Eckley, D.M., et al. J. Cell Biol. 147(2):307-320(1999)
Murdock, D.G., et al. J. Biol. Chem. 274(20):14429-14433(1999)
Ichikawa, K., et al. Gene 189(2):277-287(1997)
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