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MRPL54 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MRPL54 Antibody (Center) AP17698c
    MRPL54 Antibody (Center) (Cat. #AP17698c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MRPL54 antibody detected the MRPL54 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6P161
Other Accession NP_758455.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 64-92 aa
Additional Information
Other Names 39S ribosomal protein L54, mitochondrial, L54mt, MRP-L54, MRPL54
Target/Specificity This MRPL54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human MRPL54.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMRPL54 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MRPL54
Cellular Location Mitochondrion. EMBL; BC065273; AAH65273.1; -; mRNA CCDS; CCDS12111.1; - RefSeq; NP_758455.1; NM_172251.2 UniGene; Hs.356578; - PDB; 3J9M; EM; 3.50 A; l=1-138 PDB; 5OOL; EM; 3.06 A; l=1-138 PDB; 5OOM; EM; 3.03 A; l=1-138 PDBsum; 3J9M; - PDBsum; 5OOL; - PDBsum; 5OOM; - ProteinModelPortal; Q6P161; - SMR; Q6P161; - BioGrid; 125522; 13 CORUM; Q6P161; - IntAct; Q6P161; 8 MINT; Q6P161; - STRING; 9606.ENSP00000331849; - iPTMnet; Q6P161; - PhosphoSitePlus; Q6P161; - BioMuta; MRPL54; - DMDM; 74737109; - EPD; Q6P161; - MaxQB; Q6P161; - PaxDb; Q6P161; - PeptideAtlas; Q6P161; - PRIDE; Q6P161; - ProteomicsDB; 66822; - TopDownProteomics; Q6P161; - DNASU; 116541; - Ensembl; ENST00000330133; ENSP00000331849; ENSG00000183617 GeneID; 116541; - KEGG; hsa:116541; - UCSC; uc002lyq.5; human CTD; 116541; - EuPathDB; HostDB:ENSG00000183617.4; - GeneCards; MRPL54; - HGNC; HGNC:16685; MRPL54 HPA; HPA042117; - HPA; HPA046767; - MIM; 611858; gene neXtProt; NX_Q6P161; - OpenTargets; ENSG00000183617; - PharmGKB; PA30987; - eggNOG; KOG3435; Eukaryota eggNOG; ENOG411244M; LUCA GeneTree; ENSGT00390000001201; - HOGENOM; HOG000068097; - HOVERGEN; HBG093903; - InParanoid; Q6P161; - KO; K17435; - OMA; RLTTYAM; - OrthoDB; EOG091G0TM2; - PhylomeDB; Q6P161; - TreeFam; TF314007; - Reactome; R-HSA-5368286; Mitochondrial translation initiation Reactome; R-HSA-5389840; Mitochondrial translation elongation Reactome; R-HSA-5419276; Mitochondrial translation termination GenomeRNAi; 116541; - PRO; PR:Q6P161; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000183617; - CleanEx; HS_MRPL54; - ExpressionAtlas; Q6P161; baseline and differential Genevisible; Q6P161; HS GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome GO; GO:0005762; C:mitochondrial large ribosomal subunit; IDA:UniProtKB GO; GO:0003723; F:RNA binding; HDA:UniProtKB GO; GO:0070125; P:mitochondrial translational elongation; TAS:Reactome GO; GO:0070126; P:mitochondrial translational termination; TAS:Reactome InterPro; IPR013870; Ribosomal_L37_mit Pfam; PF08561; Ribosomal_L37; 1 1: Evidence at protein level; 3D-structure; Complete proteome; Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide TRANSIT 1 14 Mitochondrion. CHAIN 15 138 39S ribosomal protein L54, mitochondrial /FTId=PRO_0000278280 HELIX 115 132 {ECO:0000244|PDB:5OOM} SEQUENCE 138 AA; 15819 MW; 98E0FCA10592B064 CRC64; MATKRLFGAT RTWAGWGAWE LLNPATSGRL LARDYAKKPV MKGAKSGKGA VTSEALKDPD VCTDPVQLTT YAMGVNIYKE GQDVPLKPDA EYPEWLFEMN LGPPKTLEEL DPESREYWRR LRKQNIWRHN RLSKNKRL
Citations (0)

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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq].


Lamesch, P., et al. Genomics 89(3):307-315(2007)
Zhang, Z., et al. Genomics 81(5):468-480(2003)
Koc, E.C., et al. J. Biol. Chem. 276(47):43958-43969(2001)
Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995) :

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$ 295.00
$ 99.00
Cat# AP17698c
(40 western blots)
Availability: In Stock
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