|Application ||WB, E|
|Other Accession||Q2TBK5, NP_006849.1|
|Calculated MW||25206 Da|
|Antigen Region||77-104 aa|
|Other Names||Transmembrane emp24 domain-containing protein 1, Interleukin-1 receptor-like 1 ligand, Putative T1/ST2 receptor-binding protein, p24 family protein gamma-1, Tp24, p24gamma1, TMED1, IL1RL1L, IL1RL1LG|
|Target/Specificity||This TMED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-104 amino acids from the Central region of human TMED1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMED1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1). This protein lacks any similarity to other interleukin 1 ligands. The functional significance of its interaction with IL1RL1 is not known.
Tare, N., et al. Exp. Cell Res. 316(15):2527-2537(2010)
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Gayle, M.A., et al. J. Biol. Chem. 271(10):5784-5789(1996)
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