ZBTB49 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q6ZSB9 |
Other Accession | NP_660334.3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 85061 Da |
Antigen Region | 172-199 aa |
Gene ID | 166793 |
---|---|
Other Names | Zinc finger and BTB domain-containing protein 49, Zinc finger protein 509, ZBTB49, ZNF509 |
Target/Specificity | This ZBTB49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-199 amino acids from the N-terminal region of human ZBTB49. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ZBTB49 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZBTB49 |
---|---|
Synonyms | ZNF509 |
Function | Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription. |
Cellular Location | [Isoform 1]: Cytoplasm. Nucleus Note=Predominantly located in the nucleus |
Tissue Location | Highly expressed in normal epidermis and in other epithelial tissues, including in colon and lung. Tends to be down- regulated in colon, lung and skin cancer tissues |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZBTB49 may be involved in transcriptional regulation.
References
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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