|Application ||WB, E|
|Calculated MW||85061 Da|
|Antigen Region||172-199 aa|
|Other Names||Zinc finger and BTB domain-containing protein 49, Zinc finger protein 509, ZBTB49, ZNF509|
|Target/Specificity||This ZBTB49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-199 amino acids from the N-terminal region of human ZBTB49.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZBTB49 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription.|
|Cellular Location||Isoform 1: Cytoplasm. Nucleus. Note=Predominantly located in the nucleus.|
|Tissue Location||Highly expressed in normal epidermis and in other epithelial tissues, including in colon and lung. Tends to be down-regulated in colon, lung and skin cancer tissues|
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Provided below are standard protocols that you may find useful for product applications.
ZBTB49 may be involved in transcriptional regulation.
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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