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ROD1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ROD1 Antibody (N-term) AP17726A
    ROD1 Antibody (N-term) (Cat. #AP17726a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ROD1 antibody detected the ROD1 protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O95758
Other Accession Q9Z118, Q8BHD7, NP_001157262.1, NP_005147.3
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 59690 Da
Antigen Region 253-279 aa
Additional Information
Gene ID 9991
Other Names Polypyrimidine tract-binding protein 3, Regulator of differentiation 1, Rod1, PTBP3, ROD1
Target/Specificity This ROD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-279 amino acids from the N-terminal region of human ROD1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsROD1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTBP3
Synonyms ROD1
Function RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
Tissue Location Expressed in several hematopoietic cell lines examined.
Research Areas
Citations (0)
citation

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Background

ROD1 is a functional homolog of nrd1, an S. pombe RNA-binding protein that suppresses the onset of differentiation.

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :
Sadvakassova, G., et al. J. Cell. Physiol. 220(3):672-679(2009)
Yamamoto, H., et al. Mol. Cell. Biol. 19(5):3829-3841(1999)

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$ 365.00
$ 140.00
Cat# AP17726A
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