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NFKBIL2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NFKBIL2 Antibody (N-term) AP17737A
    NFKBIL2 Antibody (N-term) (Cat. #AP17737a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the NFKBIL2 antibody detected the NFKBIL2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96HA7
Other Accession NP_038460.4
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 150929 Da
Antigen Region 38-65 aa
Additional Information
Gene ID 4796
Other Names Tonsoku-like protein, Inhibitor of kappa B-related protein, I-kappa-B-related protein, IkappaBR, NF-kappa-B inhibitor-like protein 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2, TONSL, IKBR, NFKBIL2
Target/Specificity This NFKBIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human NFKBIL2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNFKBIL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms IKBR, NFKBIL2
Function Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork- associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold.
Cellular Location Cytoplasm. Nucleus. Note=Mainly nuclear. Localizes to DNA damage sites, accumulates at stressed replication forks
Tissue Location Expressed in heart, skeletal muscle and tracheal epithelial cells.
Research Areas
Citations (0)

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The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.


Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Norman, D.A., et al. Ann. Hum. Genet. 64 (PT 1), 15-23 (2000) :
Ray, P., et al. J. Biol. Chem. 270(18):10680-10685(1995)

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$ 295.00
$ 99.00
Cat# AP17737A
(40 western blots)
Availability: In Stock
Bulk Size
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