|Application ||WB, E|
|Calculated MW||59527 Da|
|Antigen Region||198-227 aa|
|Other Names||Lysophospholipid acyltransferase 2, LPLAT 2, 231-, 1-acylglycerophosphate O-acyltransferase, 1-acylglycerophosphoethanolamine O-acyltransferase, 231n7, Lysophosphatidic acid acyltransferase, LPAAT, Lyso-PA acyltransferase, Lysophosphatidylethanolamine acyltransferase, LPEAT, Lyso-PE acyltransferase, Membrane-bound O-acyltransferase domain-containing protein 2, O-acyltransferase domain-containing protein 2, MBOAT2, OACT2|
|Target/Specificity||This MBOAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the Central region of human MBOAT2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MBOAT2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3- phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2- diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in neutrophils.|
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Provided below are standard protocols that you may find useful for product applications.
Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
Tamaki, H., et al. J. Biol. Chem. 282(47):34288-34298(2007)
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