|Application ||WB, E|
|Other Accession||Q8BHC1, Q17QU4, NP_741995.1|
|Calculated MW||24622 Da|
|Antigen Region||12-40 aa|
|Other Names||Ras-related protein Rab-39B, RAB39B|
|Target/Specificity||This RAB39B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human RAB39B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB39B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in vesicular trafficking. Plays a role in synapse formation. May regulate the homeostasis of SNCA/alpha- synuclein. Together with PICK1 proposed to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR compostion at the post-synapses and thus synaptic transmission (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus Note=Partial colocalization with markers that cycle from the cell surface to the trans-Golgi network.|
|Tissue Location||Highly expressed in the brain.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking.
Giannandrea, M., et al. Am. J. Hum. Genet. 86(2):185-195(2010)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Cheng, H., et al. Cytogenet. Genome Res. 97 (1-2), 72-75 (2002) :
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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