|Application ||WB, E|
|Other Accession||Q8BHC1, Q17QU4, NP_741995.1|
|Calculated MW||24622 Da|
|Antigen Region||12-40 aa|
|Other Names||Ras-related protein Rab-39B, RAB39B|
|Target/Specificity||This RAB39B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human RAB39B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB39B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in vesicular trafficking. Plays a role in synapse formation. May regulate the homeostasis of SNCA/alpha- synuclein. Together with PICK1 proposed to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR compostion at the post-synapses and thus synaptic transmission (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus Note=Partial colocalization with markers that cycle from the cell surface to the trans-Golgi network.|
|Tissue Location||Highly expressed in the brain.|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking.
Giannandrea, M., et al. Am. J. Hum. Genet. 86(2):185-195(2010)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Cheng, H., et al. Cytogenet. Genome Res. 97 (1-2), 72-75 (2002) :
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.