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MAFG Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MAFG Antibody (N-term) AP17800A
    MAFG Antibody (N-term) (Cat. #AP17800a) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the MAFG antibody detected the MAFG protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15525
Other Accession O54790, Q90889, A5PJV0, NP_116100.2
Reactivity Human, Mouse
Predicted Bovine, Chicken
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 17850 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 4097
Other Names Transcription factor MafG, V-maf musculoaponeurotic fibrosarcoma oncogene homolog G, hMAF, MAFG
Target/Specificity This MAFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAFG.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMAFG Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF- E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+) (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:11154691}
Tissue Location Highly expressed in skeletal muscle. Also expressed in heart and brain
Research Areas
Citations (0)

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Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).


Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) :
Berg, D.T., et al. J. Biol. Chem. 282(51):36837-36844(2007)
Yamamoto, T., et al. Genes Cells 11(6):575-591(2006)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Tramier, M., et al. Biophys. J. 83(6):3570-3577(2002)

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$ 295.00
$ 99.00
Cat# AP17800A
(40 western blots)
Availability: In Stock
Bulk Size
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