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>   home   >   Products   >   Primary Antibodies   >   HNRPLL Antibody (N-term)   

HNRPLL Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HNRPLL Antibody (N-term) AP17812A
    HNRPLL Antibody (N-term) (Cat. #AP17812a) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the HNRPLL antibody detected the HNRPLL protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WVV9
Other Accession Q921F4, NP_612403.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 60083 Da
Antigen Region 132-162 aa
Additional Information
Gene ID 92906
Other Names Heterogeneous nuclear ribonucleoprotein L-like, hnRNPLL, Stromal RNA-regulating factor, HNRNPLL, HNRPLL, SRRF
Target/Specificity This HNRPLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-162 amino acids from the N-terminal region of human HNRPLL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHNRPLL Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.
Tissue Location Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.
Citations (0)

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HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).


Wu, Z., et al. J. Immunol. 185(1):231-238(2010)
Topp, J.D., et al. RNA 14(10):2038-2049(2008)
Oberdoerffer, S., et al. Science 321(5889):686-691(2008)
Lim, J., et al. Cell 125(4):801-814(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)

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$ 295.00
$ 99.00
Cat# AP17812A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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