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>   home   >   Products   >   Primary Antibodies   >   ZNF385A Antibody (N-term)   

ZNF385A Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZNF385A Antibody (N-term) AP17816a
    ZNF385A Antibody (N-term) (Cat. #AP17816a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ZNF385A antibody detected the ZNF385A protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96PM9
Other Accession Q8VD12, NP_001124439.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40454 Da
Antigen Region 57-83 aa
Additional Information
Gene ID 25946
Other Names Zinc finger protein 385A, Hematopoietic zinc finger protein, Retinal zinc finger protein, ZNF385A, HZF, RZF, ZNF385
Target/Specificity This ZNF385A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-83 amino acids from the N-terminal region of human ZNF385A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZNF385A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF385A
Synonyms HZF, RZF, ZNF385
Function RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, binds the 3'-UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti- proliferative activity. May also bind CCNB1 mRNA. Alternatively, may also regulate p53/TP53 activity through direct protein-protein interaction. Interacts with p53/TP53 and promotes cell-cycle arrest over apoptosis enhancing preferentially the DNA binding and transactivation of p53/TP53 on cell-cycle arrest target genes over proapoptotic target genes. May also regulate the ubiquitination and stability of CDKN1A promoting DNA damage-induced cell cycle arrest. Also plays a role in megakaryocytes differentiation.
Cellular Location Cytoplasm. Nucleus, nucleolus. Cell projection, dendrite. Note=Detected in dendrites of Purkinje cells and hippocampal neurons.
Tissue Location Expressed predominantly in the retina.
Citations (0)

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Zinc finger proteins, such as ZNF385A, are regulatory proteins that act as transcription factors, bind single- or double-stranded RNA, or interact with other proteins (Sharma et al., 2004 [PubMed 15527981]).


Das, S., et al. Cell 130(4):624-637(2007)
Sharma, S., et al. Gene 342(2):219-229(2004)
Kimura, Y., et al. J. Exp. Med. 195(7):941-952(2002)
Hidaka, M., et al. Mech. Dev. 90(1):3-15(2000)

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$ 295.00
$ 99.00
Cat# AP17816a
(40 western blots)
Availability: In Stock
Bulk Size
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