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SHROOM2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SHROOM2 Antibody (Center) AP17830C
    SHROOM2 Antibody (Center) (Cat. #AP17830c) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the SHROOM2 antibody detected the SHROOM2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13796
Other Accession NP_001640.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 176410 Da
Antigen Region 599-625 aa
Additional Information
Gene ID 357
Other Names Protein Shroom2, Apical-like protein, Protein APXL, SHROOM2, APXL
Target/Specificity This SHROOM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 599-625 amino acids from the Central region of human SHROOM2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSHROOM2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms APXL
Function May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity).
Cellular Location Apical cell membrane. Cell junction, tight junction. Cytoplasm, cytoskeleton. Note=Associates with cortical F-actin
Tissue Location Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas
Research Areas
Citations (0)

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The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome.


Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Dietz, M.L., et al. J. Biol. Chem. 281(29):20542-20554(2006)
Hagens, O., et al. BMC Cell Biol. 7, 18 (2006) :

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$ 295.00
$ 99.00
Cat# AP17830C
(40 western blots)
Availability: In Stock
Bulk Size
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