|Application ||WB, E|
|Other Accession||Q8BKV0, NP_001035249.1|
|Calculated MW||49429 Da|
|Antigen Region||36-63 aa|
|Other Names||Testican-3, SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3, SPOCK3, TICN3|
|Target/Specificity||This SPOCK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of human SPOCK3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SPOCK3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Expressed in brain.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 encodes a member of a novel Ca(2+)-binding proteoglycan family.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kamioka, M., et al. Leuk. Res. 33(7):913-918(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Nakada, M., et al. Cancer Res. 61(24):8896-8902(2001)
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