|Application ||WB, E|
|Other Accession||Q9QYL8, Q9WTL7, NP_009191.1|
|Calculated MW||24737 Da|
|Antigen Region||181-207 aa|
|Other Names||Acyl-protein thioesterase 2, APT-2, 312-, Lysophospholipase II, LPL-II, LysoPLA II, LYPLA2, APT2|
|Target/Specificity||This LYPLA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-207 amino acids from the C-terminal region of human LYPLA2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LYPLA2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43.|
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Provided below are standard protocols that you may find useful for product applications.
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. [provided by RefSeq].
Ma, J., et al. Atherosclerosis 191(1):63-72(2007)
Wang, A., et al. Biochim. Biophys. Acta 1439(1):1-16(1999)
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