|Application ||WB, E|
|Calculated MW||27562 Da|
|Antigen Region||10-36 aa|
|Other Names||Ras association domain-containing protein 3, RASSF3|
|Target/Specificity||This RASSF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human RASSF3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RASSF3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton Note=Localized to microtubules in vascular endothelial cells|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM].
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Jacquemart, I.C., et al. Int. J. Oncol. 34(2):517-528(2009)
Fujita, H., et al. J. Biol. Chem. 280(6):5022-5031(2005)
Tommasi, S., et al. Oncogene 21(17):2713-2720(2002)
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