THEM5 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8N1Q8 |
Other Accession | NP_872384.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27677 Da |
Antigen Region | 71-99 aa |
Gene ID | 284486 |
---|---|
Other Names | Acyl-coenzyme A thioesterase THEM5, Acyl-CoA thioesterase THEM5, Acyl-coenzyme A thioesterase 15, Thioesterase superfamily member 5, THEM5, ACOT15 |
Target/Specificity | This THEM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the Central region of human THEM5. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | THEM5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | THEM5 |
---|---|
Synonyms | ACOT15 |
Function | Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleoyl-CoA and other unsaturated long-chain fatty acid-CoA esters (PubMed:22586271). Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin (PubMed:22586271). Required for normal mitochondrial function (PubMed:22586271). |
Cellular Location | Mitochondrion matrix |
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Provided below are standard protocols that you may find useful for product applications.
Background
THEM5 is an enzyme with hydrolase activity.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
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