|Application ||WB, E|
|Calculated MW||27677 Da|
|Antigen Region||71-99 aa|
|Other Names||Acyl-coenzyme A thioesterase THEM5, Acyl-CoA thioesterase THEM5, Acyl-coenzyme A thioesterase 15, Thioesterase superfamily member 5, THEM5, ACOT15|
|Target/Specificity||This THEM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the Central region of human THEM5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||THEM5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function.|
|Cellular Location||Mitochondrion matrix|
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Provided below are standard protocols that you may find useful for product applications.
THEM5 is an enzyme with hydrolase activity.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
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