|Application ||WB, E|
|Calculated MW||37195 Da|
|Antigen Region||188-214 aa|
|Other Names||Carcinoembryonic antigen-related cell adhesion molecule 6, Non-specific crossreacting antigen, Normal cross-reacting antigen, CD66c, CEACAM6, NCA|
|Target/Specificity||This CEACAM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-214 amino acids from the Central region of human CEACAM6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CEACAM6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor.|
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Provided below are standard protocols that you may find useful for product applications.
Carcinoembryonic antigen (CEA; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD form of CEA (Barnett et al., 1988 [PubMed 3220478]). For background information on the CEA family of genes, see CEACAM1 (MIM 109770).
Wang, Y., et al. J. Clin. Invest. 119(6):1604-1615(2009)
Kolla, V., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 296 (6), L1019-L1030 (2009) :
Litkouhi, B., et al. Gynecol. Oncol. 109(2):234-239(2008)
Owaidah, T.M., et al. Hematol Oncol Stem Cell Ther 1(1):34-37(2008)
Skubitz, K.M., et al. J Transl Med 6, 78 (2008) :
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