|Application ||WB, E|
|Calculated MW||36946 Da|
|Antigen Region||74-100 aa|
|Other Names||Dolichyl-phosphate beta-glucosyltransferase, DolP-glucosyltransferase, Asparagine-linked glycosylation protein 5 homolog, ALG5|
|Target/Specificity||This ALG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-100 amino acids from the Central region of human ALG5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ALG5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in pancreas, placenta, liver, heart, brain, kidney, skeletal muscle, and lung|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the glycosyltransferase 2 family. The encoded protein participates in glucosylation of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the oligomannose core is necessary to ensure substrate recognition, and therefore, effectual transfer of the oligomannose core to the nascent glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Imbach, T., et al. Proc. Natl. Acad. Sci. U.S.A. 96(12):6982-6987(1999)
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