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ALG5 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ALG5 Antibody (Center) AP17876C
    ALG5 Antibody (Center) (Cat. #AP17876c) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the ALG5 antibody detected the ALG5 protein (arrow).
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9Y673
Other Accession NP_037470.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 36946 Da
Antigen Region 74-100 aa
Additional Information
Gene ID 29880
Other Names Dolichyl-phosphate beta-glucosyltransferase, DolP-glucosyltransferase, Asparagine-linked glycosylation protein 5 homolog, ALG5
Target/Specificity This ALG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-100 amino acids from the Central region of human ALG5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsALG5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALG5
Function Required for the assembly of lipid-linked oligosaccharides in kidney epithelial cells, and protein N-glycosylation. Required for polycystin-1 (PKD1) glycosylation and maturation.
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location Expressed in pancreas, placenta, liver, heart, brain, kidney, skeletal muscle, and lung
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the glycosyltransferase 2 family. The encoded protein participates in glucosylation of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the oligomannose core is necessary to ensure substrate recognition, and therefore, effectual transfer of the oligomannose core to the nascent glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.

References

Imbach, T., et al. Proc. Natl. Acad. Sci. U.S.A. 96(12):6982-6987(1999)

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$ 182.50
$ 70.00
Cat# AP17876C
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