|Application ||WB, E|
|Calculated MW||48963 Da|
|Antigen Region||101-130 aa|
|Other Names||Arf-GAP domain and FG repeat-containing protein 2, HIV-1 Rev-binding protein-like protein, Rev/Rex activation domain-binding protein related, RAB-R, AGFG2, HRBL, RABR|
|Target/Specificity||This AGFG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the Central region of human AGFG2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AGFG2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. The 3' UTR of this gene contains an insulin receptor substrate 3-like pseudogene.
Doria, M., et al. J. Cell Biol. 147(7):1379-1384(1999)
Glockner, G., et al. Genome Res. 8(10):1060-1073(1998)
Salcini, A.E., et al. Genes Dev. 11(17):2239-2249(1997)
Wong, W.T., et al. Proc. Natl. Acad. Sci. U.S.A. 92(21):9530-9534(1995)
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