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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CENPO Antibody (N-term)   

CENPO Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CENPO Antibody (N-term) AP17884a
    CENPO Antibody (N-term) (Cat. #AP17884a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CENPO antibody detected the CENPO protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BU64
Other Accession NP_077298.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33786 Da
Antigen Region 42-69 aa
Additional Information
Gene ID 79172
Other Names Centromere protein O, CENP-O, Interphase centromere complex protein 36, CENPO, ICEN36, MCM21R
Target/Specificity This CENPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-69 amino acids from the N-terminal region of human CENPO.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCENPO Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ICEN36, MCM21R
Function Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex.
Cellular Location Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex
Research Areas
Citations (0)

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CENPO is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
Saito, A., et al. J. Rheumatol. 36(4):781-786(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Izuta, H., et al. Genes Cells 11(6):673-684(2006)

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$ 295.00
$ 99.00
Cat# AP17884a
(40 western blots)
Availability: In Stock
Bulk Size
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