|Application ||WB, E|
|Calculated MW||26458 Da|
|Antigen Region||136-165 aa|
|Other Names||MICOS complex subunit MIC25, Coiled-coil-helix cristae morphology protein 1, Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, CHCHD6, CHCM1, MIC25|
|Target/Specificity||This CHCHD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the Central region of human CHCHD6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CHCHD6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|
|Cellular Location||Mitochondrion inner membrane; Lipid-anchor. Mitochondrion|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Xie, J., et al. FEBS Lett. 581(18):3545-3549(2007)
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