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ALG13 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NP73 |
| Other Accession | Q9D8C3, NP_001161857.1, NP_001034299.3 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 126056 Da |
| Antigen Region | 44-70 aa |
| Gene ID | 79868 |
|---|---|
| Other Names | Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13, Asparagine-linked glycosylation 13 homolog, Glycosyltransferase 28 domain-containing protein 1, UDP-N-acetylglucosamine transferase subunit ALG13 homolog, ALG13, CXorf45, GLT28D1 |
| Target/Specificity | This ALG13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-70 amino acids from the Central region of human ALG13. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ALG13 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ALG13 |
|---|---|
| Synonyms | CXorf45, GLT28D1 |
| Function | [Isoform 1]: Possible multifunctional enzyme with both glycosyltransferase and deubiquitinase activities. |
| Cellular Location | [Isoform 2]: Endoplasmic reticulum. Note=Could be recruited to the cytosolic face of the endoplasmic reticulum membrane through its interaction with ALG14 |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene.
References
Averbeck, N., et al. J. Biol. Chem. 282(40):29081-29088(2007)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Gao, X.D., et al. J. Biol. Chem. 280(43):36254-36262(2005)
Epplen, C., et al. Hum. Genet. 93(1):35-41(1994)
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