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PNMA3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UL41 |
| Other Accession | NP_037496.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 52376 Da |
| Antigen Region | 384-412 aa |
| Gene ID | 29944 |
|---|---|
| Other Names | Paraneoplastic antigen Ma3, PNMA3, MA3 |
| Target/Specificity | This PNMA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-412 amino acids from the C-terminal region of human PNMA3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PNMA3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PNMA3 |
|---|---|
| Synonyms | MA3 |
| Cellular Location | Nucleus, nucleolus. |
| Tissue Location | Expressed at high levels in the brain and testis. Expressed at lower levels in the heart, trachea and kidney |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. [provided by RefSeq].
References
Wills, N.M., et al. J. Biol. Chem. 281(11):7082-7088(2006)
Schuller, M., et al. J. Neuroimmunol. 169 (1-2), 172-176 (2005) :
Rosenfeld, M.R., et al. Ann. Neurol. 50(3):339-348(2001)
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