SLC4A9 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q96Q91 |
Other Accession | NP_113655.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 108248 Da |
Antigen Region | 2-30 aa |
Gene ID | 83697 |
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Other Names | Anion exchange protein 4, AE 4, Anion exchanger 4, Sodium bicarbonate cotransporter 5, Solute carrier family 4 member 9, SLC4A9, AE4, SBC5 |
Target/Specificity | This SLC4A9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-30 amino acids from the N-terminal region of human SLC4A9. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SLC4A9 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SLC4A9 (HGNC:11035) |
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Function | Electroneutral Cl(-)/HCO3(-) antiporter that favors chloride ion entry and efflux of hydrogencarbonate and sodium ion across the basolateral membrane and may participate in salivary secretion (PubMed:27114614). Also mediates Cl(-)/HCO3(-) exchange activity in the presence of K(+) as well as Cs(+), Li(+), and Rb(+) (By similarity). Does not contribute to Cl(-)/HCO3(-) exchanger in the apical membrane of the upper villous epithelium (By similarity). |
Cellular Location | Basolateral cell membrane {ECO:0000250|UniProtKB:A0A494BA31}; Multi-pass membrane protein. Note=Localized in the basolateral membrane of the cortical collecting duct (CCD)and submandibular gland (SMG) duct {ECO:0000250|UniProtKB:A0A494BA31} |
Tissue Location | Kidney specific. {ECO:0000269|PubMed:11305939, ECO:0000269|Ref.7} |
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Provided below are standard protocols that you may find useful for product applications.
Background
SLC4A9 is probable apical anion exchanger of the kidney cortex (By similarity).
References
Parker, M.D., et al. Biochem. Biophys. Res. Commun. 282(5):1103-1109(2001)
Lipovich, L., et al. Genome Biol. 2 (4), RESEARCH0011 (2001) :
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