|Application ||WB, E|
|Other Accession||P97554, Q9QYI6, NP_036460.1|
|Calculated MW||25518 Da|
|Antigen Region||40-69 aa|
|Other Names||DnaJ homolog subfamily B member 9, Endoplasmic reticulum DNA J domain-containing protein 4, ER-resident protein ERdj4, ERdj4, Microvascular endothelial differentiation gene 1 protein, Mdg-1, DNAJB9, MDG1|
|Target/Specificity||This DNAJB9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human DNAJB9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DNAJB9 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a co-chaperone with an Hsp70 protein.|
|Cellular Location||Endoplasmic reticulum lumen.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. This gene is a member of the type 2 subgroup of DnaJ proteins. The encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum stress and plays a role in protecting stressed cells from apoptosis.
Zhang, H.M., et al. J. Virol. 84(17):8446-8459(2010)
Lenna, S., et al. J. Immunol. 184(9):4654-4661(2010)
McLaughlin, M., et al. J. Biol. Chem. 285(10):6960-6969(2010)
Wang, M., et al. J. Biol. Chem. 284(48):33377-33383(2009)
Colombo, F., et al. Int. J. Cancer 124(9):2179-2185(2009)
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