|Application ||WB, E|
|Calculated MW||70861 Da|
|Antigen Region||528-555 aa|
|Other Names||RING finger protein 207, RNF207, C1orf188|
|Target/Specificity||This RNF207 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 528-555 amino acids from the C-terminal region of human RNF207.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RNF207 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.|
|Cellular Location||Cytoplasm. Note=Probably located in the endoplasmic reticulum and/or possibly the cis-Golgi apparatus.|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Pfeufer, A., et al. Nat. Genet. 41(4):407-414(2009)
Newton-Cheh, C., et al. Nat. Genet. 41(4):399-406(2009)
Wistow, G., et al. Mol. Vis. 8, 171-184 (2002) :
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