|Application ||WB, E|
|Other Accession||P59279, NP_116235.2|
|Calculated MW||24214 Da|
|Antigen Region||105-131 aa|
|Other Names||Ras-related protein Rab-2B, RAB2B|
|Target/Specificity||This RAB2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-131 amino acids from the Central region of human RAB2B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB2B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for protein transport from the endoplasmic reticulum to the Golgi complex.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane. Golgi apparatus membrane|
|Tissue Location||Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte|
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Provided below are standard protocols that you may find useful for product applications.
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM].
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Fu, G.K., et al. Genomics 84(1):205-210(2004)
Ni, X., et al. J. Hum. Genet. 47(10):548-551(2002)
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