TMEM178 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8NBL3 |
Other Accession | Q68FV0, Q9CZ16, Q08CE6, NP_689603.2 |
Reactivity | Human, Mouse |
Predicted | Zebrafish, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 33019 Da |
Antigen Region | 128-156 aa |
Gene ID | 130733 |
---|---|
Other Names | Transmembrane protein 178A, TMEM178A, TMEM178 |
Target/Specificity | This TMEM178 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-156 amino acids from the Central region of human TMEM178. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TMEM178 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TMEM178A |
---|---|
Synonyms | TMEM178 |
Function | Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. |
Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9CZ16}; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Terracciano, A., et al. Mol. Psychiatry (2008) In press :
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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