|Application ||WB, E|
|Other Accession||A7MBC0, NP_001139287.1|
|Calculated MW||43748 Da|
|Antigen Region||137-164 aa|
|Other Names||Putative N-acetylglucosamine-6-phosphate deacetylase, Amidohydrolase domain-containing protein 2, GlcNAc 6-P deacetylase, AMDHD2|
|Target/Specificity||This AMDHD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the Central region of human AMDHD2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AMDHD2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.|
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Provided below are standard protocols that you may find useful for product applications.
Belongs to the nagA family.
Brandenberger, R., et al. Nat. Biotechnol. 22(6):707-716(2004)
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
Lai, C.H., et al. Genome Res. 10(5):703-713(2000)
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