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CPNE5 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CPNE5 Antibody (C-term) AP17963b
    CPNE5 Antibody (C-term) (Cat. #AP17963b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CPNE5 antibody detected the CPNE5 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9HCH3
Other Accession Q8JZW4, NP_065990.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 65734 Da
Antigen Region 509-535 aa
Additional Information
Gene ID 57699
Other Names Copine-5, Copine V, CPNE5, KIAA1599
Target/Specificity This CPNE5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 509-535 amino acids from the C-terminal region of human CPNE5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCPNE5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPNE5 (HGNC:2318)
Function Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Cellular Location Perikaryon {ECO:0000250|UniProtKB:Q8JZW4}. Cell projection {ECO:0000250|UniProtKB:Q8JZW4}
Tissue Location Expressed in the brain, heart, stomach, spleen, lymph node and testis (PubMed:12949241). Expressed in melanocytes (PubMed:23999003).
Research Areas
Citations (0)
citation

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Background

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Sequence analysis identified multiple alternatively spliced transcript variants but their full-length natures could not be determined.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Tripodis, N., et al. Genome Res. 8(6):631-643(1998)
Creutz, C.E., et al. J. Biol. Chem. 273(3):1393-1402(1998)

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$ 182.50
$ 70.00
Cat# AP17963b
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