|Application ||WB, E|
|Calculated MW||35548 Da|
|Antigen Region||211-237 aa|
|Other Names||Serine/threonine-protein phosphatase CPPED1, Calcineurin-like phosphoesterase domain-containing protein 1, Complete S-transactivated protein 1, CPPED1, CSTP1|
|Target/Specificity||This CPPED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-237 amino acids from the C-terminal region of human CPPED1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CPPED1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.|
|Tissue Location||Expressed in subcutaneous adipose tissue.|
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Provided below are standard protocols that you may find useful for product applications.
Belongs to the metallophosphoesterase superfamily. CPPED1 family.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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