|Application ||WB, E|
|Calculated MW||24279 Da|
|Antigen Region||116-142 aa|
|Other Names||GrpE protein homolog 1, mitochondrial, HMGE, Mt-GrpE#1, GRPEL1, GREPEL1|
|Target/Specificity||This GRPEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-142 amino acids from the Central region of human GRPEL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GRPEL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.
Borges, J.C., et al. J. Biol. Chem. 278(37):35337-35344(2003)
Choglay, A.A., et al. Gene 267(1):125-134(2001)
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