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GRPEL1 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GRPEL1 Antibody (Center) AP17977c
    GRPEL1 Antibody (Center) (Cat. #AP17977c) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the GRPEL1 antibody detected the GRPEL1 protein (arrow).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9HAV7
Other Accession NP_079472.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 24279 Da
Antigen Region 116-142 aa
Additional Information
Gene ID 80273
Other Names GrpE protein homolog 1, mitochondrial, HMGE, Mt-GrpE#1, GRPEL1, GREPEL1
Target/Specificity This GRPEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-142 amino acids from the Central region of human GRPEL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGRPEL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRPEL1
Synonyms GREPEL1
Function Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (PubMed:11311562).
Cellular Location Mitochondrion matrix
Research Areas
Citations (0)
citation

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Background

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.

References

Borges, J.C., et al. J. Biol. Chem. 278(37):35337-35344(2003)
Choglay, A.A., et al. Gene 267(1):125-134(2001)

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$ 182.50
$ 70.00
Cat# AP17977c
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