GRPEL1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9HAV7 |
Other Accession | NP_079472.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 24279 Da |
Antigen Region | 116-142 aa |
Gene ID | 80273 |
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Other Names | GrpE protein homolog 1, mitochondrial, HMGE, Mt-GrpE#1, GRPEL1, GREPEL1 |
Target/Specificity | This GRPEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-142 amino acids from the Central region of human GRPEL1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GRPEL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GRPEL1 |
---|---|
Synonyms | GREPEL1 |
Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (PubMed:11311562). |
Cellular Location | Mitochondrion matrix |
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Provided below are standard protocols that you may find useful for product applications.
Background
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.
References
Borges, J.C., et al. J. Biol. Chem. 278(37):35337-35344(2003)
Choglay, A.A., et al. Gene 267(1):125-134(2001)
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