|Application ||WB, E|
|Calculated MW||46417 Da|
|Antigen Region||72-98 aa|
|Other Names||Inositol hexakisphosphate kinase 3, InsP6 kinase 3, Inositol hexaphosphate kinase 3, IP6K3, IHPK3|
|Target/Specificity||This IP6K3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-98 amino acids from the N-terminal region of human IP6K3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IP6K3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.|
|Tissue Location||Detected in brain.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript variants encoding the same protein.
Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :
Saiardi, A., et al. J. Biol. Chem. 276(42):39179-39185(2001)
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