|Application ||WB, E|
|Calculated MW||41581 Da|
|Antigen Region||201-228 aa|
|Other Names||Putative C->U-editing enzyme APOBEC-4, 354-, Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4, APOBEC4, C1orf169|
|Target/Specificity||This APOBEC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-228 amino acids from the Central region of human APOBEC4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||APOBEC4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Putative C to U editing enzyme whose physiological substrate is not yet known.|
|Tissue Location||Predominantly expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq].
Prochnow, C., et al. Sci. China, C, Life Sci. 52(10):893-902(2009)
Rogozin, I.B., et al. Cell Cycle 4(9):1281-1285(2005)
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