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GNMT Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GNMT Antibody (Center) AP18057c
    Anti-GNMT Antibody (Center) at 1:1000 dilution + human liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14749
Other Accession Q29513, Q29555, NP_061833.1
Reactivity Human
Predicted Pig, Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32742 Da
Antigen Region 78-106 aa
Additional Information
Gene ID 27232
Other Names Glycine N-methyltransferase, GNMT
Target/Specificity This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the Central region of human GNMT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGNMT Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Cellular Location Cytoplasm.
Tissue Location Abundant in liver.
Research Areas
Citations (0)

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The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).


Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Lee, C.M., et al. Gene 443 (1-2), 151-157 (2009) :
Boyles, A.L., et al. Genet. Epidemiol. 33(3):247-255(2009)
Yen, C.H., et al. Toxicol. Appl. Pharmacol. 235(3):296-304(2009)
Franke, B., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 85(3):216-226(2009)

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$ 295.00
$ 99.00
Cat# AP18057c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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